Bone Regeneration and Growth Factors in Implant Dentistry


Localized alveolar ridge defects are a significant challenge for the clinician when the end point goal of therapy is to rehabilitate the patient’s missing dentition with an implant supported prosthesis.

Various surgical techniques and bone grafting materials have been proposed to enhance bone volume. Tissue engineering offers a viable and attractive alternative to current treatment modalities for the surgical management of severe jawbone atrophy. Currently, three recombinant human protein products have been cleared by the FDA. They are recombinant human platelet derived growth factor-bb (rhPDGF-BB), recombinant human bone morphogenetic protein-2 (rhBMP-2) and recombinant human bone morphogenetic protein-7 (rhBMP-7). They appear to accelerate the healing process and enhance tissue regeneration in challenging anatomical environments.

This presentation will share our current knowledge and clinical experiences with different biomaterials in combination with growth factors that can be utilized to achieve both horizontal and vertical ridge augmentations.

Curriculum Vitae

David Kim, USA

Dr. Kim received his dental degree (D.D.S.) from the University of Maryland Dental School, and completed his periodontology training and Doctor of Medical Science (D.M.Sc.) in oral biology from the Harvard School of Dental Medicine. Currently, as an Associate Professor at the Harvard School of Dental Medicine, he is also the Director of the Postgraduate Program in Periodontology and the Continuing Education at the Harvard School of Dental Medicine.

Dr. Kim is a past recipient of the Joseph L. Henry Award recognizing excellence in research and clinical training from Harvard. In addition, he received Balint Orban Research Award, Award for Outstanding Teaching and Mentoring in Periodontics, and Teaching Fellowship from the American Academy of Periodontology.

Dr. Kim’s clinical and research interests have been on the use of innovative concepts, technologies and biomaterials to enhance intraoral soft and hard tissue formation, especially by incorporating the tissue engineering concept to repair and regenerate soft and hard tissue volume for patients requiring dental implants to replace missing teeth. His reputation as a clinical expert in this field is reflected in his research grants, published manuscripts (81) and book chapters (21) and invited lectures at the local, national and international levels. In addition, he also uses his editorial skills as an ad hoc reviewer, consultant, and peer review panel for many well-respected journals.

He is a diplomat of the American Board of Periodontology and maintains a clinical practice in Boston, Massachusetts.